2014, Vol. 2, Issue 1, Part A

author(s)
S.K.Gangai Abirami*, Dr.P.Nirmala

abstract
Aromatic plants of Lamiaceae family are known for its traditional medicine. The leaves of the plants are promoted in relieving sore throats, toothaches, colds, coughs, laryngitits, bronchitis, nasal congestion and inflammation of the mouth and throat. Ethanolic extracts of Mentha piperita, Ocimum basilicum and Coleus aromaticus were studied for the invitro cytotoxicity against Human Laryngeal epidermoid carcinoma (Hep-2 cell lines). The results showed that Mentha piperita treated Hep-2 cell lines with maximum cytotoxicity,Ocimum basilicum shown moderate cytotoxicity . When compared to the above two plants the Coleus aromaticus treated Hep-2 cells has very little or no cytotoxicity. The findings of the present investigation demonstrated that Mentha piperitasignificantly suppresses growth and induces apoptosis in Hep-2 cell lines.